Thermo Fisher Scientific LOX Monoclonal Antibody (OTI6B11), TrueMAB
인간 LOX 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. Affinity chromatography로 정제된 액상 형태이며, 고순도와 안정성을 제공합니다. 세포 발달, 종양 억제 및 전이 연구에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase belonging to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays an essential role in the formation and repair of the extracellular matrix.
LOX functions in developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it crucial for hypoxia-induced metastasis and a valuable therapeutic target for preventing and treating metastases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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