Thermo Fisher Scientific AKR1B15 Polyclonal Antibody
Human AKR1B15 단백질의 C-말단 영역을 표적으로 하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, 고순도 Affinity Chromatography로 정제됨. PBS + sucrose buffer로 안정화되어 있으며 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested at 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human AKR1B15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691364 |
Product Specific Information
This target displays homology in the following species:
Cow: 92%
Dog: 86%
Guinea Pig: 93%
Human: 100%
Mouse: 93%
Rabbit: 86%
Rat: 100%
Yeast: 79%
Zebrafish: 86%
Target Information
Catalyzes the NADPH-dependent reduction of a variety of carbonyl substrates, including aromatic aldehydes, alkenals, ketones, and alpha-dicarbonyl compounds (PubMed:26222439, PubMed:21276782).
Also catalyzes the reduction of androgens and estrogens with high positional selectivity (17-beta-hydroxysteroid dehydrogenase activity) and 3-keto-acyl-CoAs (PubMed:25577493).
Displays strong enzymatic activity toward all-trans-retinal and 9-cis-retinal (PubMed:26222439), suggesting a physiological role in retinoid metabolism (PubMed:26222439).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-70862_AKR1B15_C9JRZ8-1_Rabbit.svg)
(이미지: PA5-70862_AKR1B15_C9JRZ8-1_Rabbit_PDP.jpeg)
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