Thermo Fisher Scientific PARN Polyclonal Antibody
Rabbit polyclonal antibody against human PARN (Poly(A)-Specific Ribonuclease). Suitable for WB and IP applications. Liquid form, unconjugated, 1 mg/mL concentration. Recommended shelf life of 1 year, stored at 4°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 539 and 589 of human Poly(A)-Specific Ribonuclease (Deadenylation Nuclease) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
The protein encoded by this gene is a 3′-exoribonuclease, similar to the RNase D family of 3′-exonucleases. It prefers poly(A) as substrate, efficiently degrading poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in eukaryotic mRNA decay.
This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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