Thermo Fisher Scientific SPDYA Polyclonal Antibody
Thermo Fisher Scientific의 SPDYA 폴리클로날 항체로 인간 SPDYA 단백질을 특이적으로 인식합니다. Western blot 및 ELISA에 적합하며, 고순도의 친화 크로마토그래피 정제 항체입니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5110420
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Concentration: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–313 of human SPDYA (NP_877433.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855831 |
Product Specific Information
Immunogen sequence:
MRHNQMCCET PPTVTVYVKS GSNRSHQPKK PITLKRPICK DNWQAFEKNT HNNNKSKRPK GPCLVIQRQD MTAFFKLFDD DLIQDFLWMD CCCKIADKYL LAMTFVYFKR AKFTISEHTR INFFIALYLA NTVEEDEEET KYEIFPWALG KNWRKLFPNF LKLRDQLWDR IDYRAIVSRR CCEEVMAIAP THYIWQRERS VHHSGAVRNY NRDEVQLPRG PSATPVDCSL CGKKRRYVRL GLSSSSSLSS HTAGVTEKHS QDSYNSLSMD IIGDPSQAYT GSEVVNDHQS NKGKKTNFLK KDKSMEWFTG SEE
Target Information
Speedy A (SPDYA), also known as SPDY1, Ringo3, or SPY1, is a 313 amino acid nuclear protein belonging to the speedy/ringo family. It is highly expressed in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver, spleen, and placenta. Speedy A regulates the G1/S phase transition of the cell cycle by binding to and activating Cdc2 p34, Cdk2, and p27. It also mediates cell survival during DNA damage, indicating a role in proper cell cycle progression. Multiple isoforms exist due to alternative splicing. The gene maps to human chromosome 2, which encodes over 1,400 genes and represents nearly 8% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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