Thermo Fisher Scientific PD-L1 Humanized Recombinant Human Monoclonal Antibody (SAA2018)
PD-L1 Humanized Recombinant Human Monoclonal Antibody (SAA2018)은 인간 PD-L1을 표적으로 하는 재조합 단일클론 항체입니다. Western blot과 ELISA에 사용 가능하며, CHO 세포에서 발현된 VHH-hFc 형식의 항체입니다. Protein A/G로 정제되었으며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Human / VHH-hFc |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA2018 |
| Immunogen | Recombinant Human CD274/PD-L1/B7-H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described member of the B7 family. PD-L1 binds to programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling. Upon binding to PD-1, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant on many murine and human cancers and can be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 may play an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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