Thermo Fisher Scientific ERCC1 Monoclonal Antibody (OTI2B4), TrueMAB
ERCC1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2B4). Western blot과 IHC(Paraffin)에 최적화. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer. DNA 손상 복구 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B4 |
| Immunogen | Full length human recombinant protein of human ERCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. It works with SLX4 in the first step of interstrand cross-link (ICL) repair and participates in processing DNA structures that can lead to cytokinesis failure if unresolved. ERCC1 is also required for homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Source: Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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