Thermo Fisher Scientific Fibrinogen gamma Polyclonal Antibody
Fibrinogen gamma 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, IP 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫드, 소에 반응하며, 고순도 항원 친화 크로마토그래피로 정제됨. 연구용으로 혈액 응고 관련 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:20,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment containing amino acids 1–405 (P02679) of Fibrinogen gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.77 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154335 |
Product Specific Information
- Recommended positive controls: HepG2, human plasma, HepG2 sup., mouse plasma, rat plasma
- Predicted reactivity: Mouse (85%), Rat (85%), Pig (84%), Bovine (82%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the major component of blood clots. Various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types. Mutations in this gene can lead to disorders such as dysfibrinogenemia, hypofibrinogenemia, and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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