Thermo Fisher Scientific MST1R Monoclonal Antibody (1H8)
Human MST1R(RON) 단백질을 인식하는 Mouse IgG2a 형 단일클론 항체로, ELISA에 적합하며 높은 특이성과 순도를 제공. Affinity chromatography로 정제된 액상 형태이며, 연구용으로 세포 증식 및 이동 관련 MST1R 신호 연구에 활용 가능.
- 판매단위
- pk
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Applications
- ELISA (ELISA)
Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1H8 |
| Immunogen | MST1R (NP_002438, 26 a.a. ~125 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
DWQCPRTPYA ASRDFDVKYV VPSFSAGGLV QAMVTYEGDR NESAVFVAIR NRLHVLGPDL KSVQSLATGP AGDPGCQTCA ACGPGPHGPP GDTDTKVLVLTarget Information
MST1R (RON) is a receptor tyrosine kinase involved in cell proliferation and motility. The protein is a membrane-spanning, disulfide-linked heterodimer, resulting from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits. Ligand binding induces tyrosine phosphorylation of the beta chain. Knockout studies show MST1R/RON (-/-) mice fail to survive past the periimplantation period. The MST1R/RON gene is mapped to 3p21, a region often deleted or mutated in small cell lung and renal carcinoma, and is implicated in epithelial cancer progression. MST1R/Ron expression is documented in many normal human tissues, with ESTs isolated from normal and cancerous colon, prostate, stomach, and uterus libraries.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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