Thermo Fisher Scientific TTLL12 Monoclonal Antibody (OTI2H10), TrueMAB
TTLL12 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체로, WB, IHC(P), Flow Cytometry에 적합. 인간 시료 반응성, 정제된 항체로 1 mg/mL 농도. 암 연구 등 TTLL12 관련 단백질 발현 분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H10 |
| Immunogen | Full length human recombinant protein of human TTLL12 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein containing one TTL domain. Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized. It is highly expressed in metastatic prostate cancer cell lines and considered a potential tumor therapy target. Overexpression may alter chromosome ploidy, while downregulation affects tubulin post-translational modifications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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