Thermo Fisher Scientific RPS10 Polyclonal Antibody
RPS10 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. Human, Mouse, Rat에 반응하며 Protein A 및 항원 친화 크로마토그래피로 정제됨. 0.62 mg/mL 농도의 액상 형태로, 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:25 |
| Flow Cytometry (Flow) | 1:25 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 96–129 from human RPS10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.62 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718157 |
Target Information
Ribosomes are organelles that catalyze protein synthesis, composed of a small subunit (40S) and a large subunit (60S) containing over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families with processed pseudogenes and one functional intron-containing gene.
Ribosomal Protein S10 (RPS10) is a 165 amino acid component of the small ribosomal 40S subunit. While generally found in the cytoplasm, RPS10 can localize to the granular component (GC) region of the nucleolus. This localization requires methylation by PRMT5 and interaction with NPS1. Defects in RPS10 are associated with Diamond-Blackfan anemia type 9 (DBA9), a congenital non-regenerative hypoplastic anemia presenting early in infancy, characterized by macrocytic anemia, erythroblastopenia, and increased malignancy risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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