Thermo Fisher Scientific FGFR1OP Recombinant Rabbit Monoclonal Antibody (2T2F9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2T2F9

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 300-399 of human CEP43. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FGFR1OP,uniProtId:O95684-1,ncbiNodeId:9606,antigenRange:300-399,antigenLength:399,antigenImageFileName:MA5-55406_FGFR1OP_O95684-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55406_FGFR1OP_O95684-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.75 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: PSLKDSESKR GNTVLKDLKL ISDKIGSLGL GTGEDDDYVD DFNSTSHRSE KSEISIGEEI EEDLSVEIDD INTSDKLDDL TQDLTVSQLS DVADYLEDVA

Target Information

This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.