Thermo Fisher Scientific CYP7B1 Polyclonal Antibody
인간 CYP7B1 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P)에서 1:500~1:1,000 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 완충액에 보관. 약물 대사 및 콜레스테롤 대사 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CYP7B1. Recombinant protein control fragment (Product # RP-91048) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640337 |
Product Specific Information
Immunogen sequence:
VRDEIDRLLQ STGQKKGSGF PIHLTREQLD SLICLESSIF EALRLSSYST TIRFVEEDLT LSSETGDYCV RKGDLVAIFP PVLHGDPEIF EAPEEFRYDR FIEDGKKKTT FFKRGKKLKC YLMPFGTGTS KC
Highest antigen sequence identity to the following orthologs:
- Mouse: 70%
- Rat: 69%
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids.
This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, converting cholesterol to bile acids.
The enzyme likely plays a minor role in total bile acid synthesis but may also be involved in the development of atherosclerosis, neurosteroid metabolism, and sex hormone synthesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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