Thermo Fisher Scientific SLC39A3 Polyclonal Antibody
SLC39A3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol 버퍼에 보관. 인간 시료에 반응하며 연구용으로 적합.
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- PA563582
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC39A3. Recombinant protein control fragment (Product # RP-104521) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647503 |
Product Specific Information
Immunogen sequence:
LPVKIIETDF EKAHRSKKIL S
Highest antigen sequence identity:
- Mouse: 81%
- Rat: 86%
Target Information
The zinc transporter ZIP3 (SLC39A3) belongs to a family of divalent ion transporters. Zinc is essential for cellular growth, development, and differentiation. ZIP3 knockout mice show no phenotypic differences compared to wild-type, but combined ZIP1–3 knockouts under zinc-deficient conditions exhibit developmental abnormalities, indicating a noncompensatory role for ZIP1–3 proteins in zinc deficiency. ZIP2 and ZIP3 are downregulated in human prostate adenocarcinoma, suggesting their role in zinc retention within cells.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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