Thermo Fisher Scientific ABHD8 Polyclonal Antibody
Human ABHD8 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABHD8. Recombinant protein control fragment (Product # RP-95836) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637560 |
Product Specific Information
Immunogen sequence:
RQGAKEKQLL KEGNAFNVSS FVLRAMMSGQ YWPEGDEVYH AELTVPVLLV HGMHDKFVPV EEDQRMAEIL LLAFLKLIDE GSHMVMLECP ETV
Antigen sequence identity:
- Mouse: 99%
- Rat: 99%
Target Information
The alpha/beta hydrolase superfamily comprises diverse members involved in important biochemical processes and related to various diseases. Despite differing sequences, substrates, and catalytic activities, they share the canonical alpha/beta hydrolase fold, consisting of an eight-stranded parallel alpha/beta structure.
These enzymes typically contain a catalytic triad composed of a histidine, an acid, and a nucleophile. Members of this superfamily are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.
The alpha/beta hydrolase domain containing (ABHD) gene subfamily includes 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD8 is a 439 amino acid protein belonging to this superfamily.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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