Thermo Fisher Scientific CD61 Monoclonal Antibody (F11), PE

Applications

• Flow Cytometry (Flow): 5 µL for 1×10⁶ cells

Product Specifications

Product Specific Information

Mouse anti-rat CD61, clone F11, recognizes both human and rat CD61 antigen.
Handling, incubation, and analysis should be performed under dim light.
Cells should be analyzed within 18 hours of staining.
If the reagent is diluted, only the quantity needed for one week should be prepared.

Target Information

CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets, and their precursors.
It functions in platelet aggregation and acts as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin.
CD61 (105 kDa) associates with either alpha IIb integrin (CD41) or alpha V integrin (CD51) at the cell surface.
It is expressed on platelets, megakaryocytes, endothelial cells, monocytes, and osteoclasts.
CD61 participates in cell adhesion and cell-surface mediated signaling.
Diseases associated with CD61 dysfunction include Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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