Thermo Fisher Scientific PSF/SFPQ Polyclonal Antibody
SFPQ(PSF) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 및 마우스 반응성, IHC 및 IHC(Paraffin)에 적합. 액상 형태로 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 657 and 707 of Human Polypyrimidine tract-binding protein-associated-splicing factor (Splicing factor, proline- and glutamine-rich) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 50 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Rat, X. tropicalis, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea pig, Panda, Orangutan, Monkey, and Gorilla based on 100% sequence identity
Target Information
SFPQ, also named PSF, encodes a nuclear factor involved in splicing and regulation of gene expression. It likely forms a heteromer with NONO and participates in DNA pairing and repair. Recent studies show SFPQ as a downstream target of tau, with nuclear depletion and cytoplasmic accumulation in Alzheimer’s disease (AD) brains. Reduced SFPQ levels may correlate with tau pathology, suggesting its role in neurodegenerative diseases including AD. SFPQ protein may appear as 47 kDa, 52 kDa, or 100 kDa molecules in various cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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