Thermo Fisher Scientific DUSP5 Monoclonal Antibody (OTI2F8), TrueMAB
DUSP5 단백질을 인식하는 Mouse monoclonal 항체로, Western blot에 적합합니다. Human 시료에 반응하며, Affinity chromatography로 정제된 액상 형태입니다. PBS/BSA/glycerol buffer에 보관되며, -20°C에서 보존 권장됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 125–384 of human DUSP5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase (MAPK) superfamily, which are associated with cellular proliferation and differentiation. Different members of this phosphatase family show distinct substrate specificities for various MAP kinases, tissue distribution, subcellular localization, and inducibility by extracellular stimuli. This gene product inactivates ERK1, is expressed in multiple tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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