Thermo Fisher Scientific MZB1 Polyclonal Antibody
MZB1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(F/P) 실험에 적합합니다. 인간 및 마우스 반응성이 있으며, 항원 친화 크로마토그래피로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific MZB1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 1–189 of PACAP (Uniprot ID: Q8WU39) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.48 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11152981 |
Product Specific Information
- Recommended positive controls: Molt-4, Raji
- Predicted reactivity: Rhesus Monkey (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. It may act as a molecular chaperone or oxidoreductase. Isoform 2 could be involved in regulation of apoptosis. MZB1 helps diversify peripheral B-cell functions by regulating calcium stores, antibody secretion, and integrin activation.
Additionally, MZB1 acts as a hormone-regulated adipokine/proinflammatory cytokine implicated in chronic inflammation, cellular expansion, and insulin resistance onset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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