Thermo Fisher Scientific RBBP6 Polyclonal Antibody
RBBP6 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 비결합(Unconjugated) 액상 형태이며 1 mg/mL 농도로 제공됩니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 to 100 of Human E3 ubiquitin-protein ligase RBBP6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
This gene encodes a cilia-associated protein belonging to the kinesin family. It plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as:
- A negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand.
- A positive regulator by preventing the processing of GLI3 into its repressor form.
Mutations in this gene have been associated with various ciliopathies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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