Thermo Fisher Scientific ACE Recombinant Rabbit Monoclonal Antibody (2H8)

Applications and Tested Dilution

Product Specifications

Target Information

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide, angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system.

Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with levels of circulating enzyme or cardiovascular pathophysiologies. Two abundant alternatively spliced variants encode the somatic and testicular forms, both equally active. Additional alternatively spliced variants have been identified, though their full-length nature remains undetermined.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.