Thermo Fisher Scientific TTF-1/NKX2.1 (Thyroid and Lung Epithelial Marker) Monoclonal Antibody (8G7G3/1)
TTF-1/NKX2.1 단클론 항체로 갑상선 및 폐 상피세포 마커 검출에 사용. IHC, ICC, Flow Cytometry 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. Protein A/G 정제, 액상 형태로 4°C 보관.
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Thermo Fisher Scientific TTF-1/NKX2.1 (Thyroid and Lung Epithelial Marker) Monoclonal Antibody (8G7G3/1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8G7G3/1 |
| Immunogen | Rat full length TTF-1 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes, but also regulates genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be linked to thyroid cancer. Multiple transcript variants encoding different isoforms have been identified.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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