Thermo Fisher Scientific NeuroD1 Polyclonal Antibody
NeuroD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. 인간 NeuroD1(aa 26–81) 합성 펩타이드를 면역원으로 사용하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 26–81 of Human NeuroD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.53 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C; avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549677 |
Product Specific Information
- Recommended positive controls: NT2D1, U87-MG, SK-N-SH
- Predicted reactivity: Xenopus laevis (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly before opening the vial.
Target Information
NeuroD1 is a transcriptional activator functioning as a differentiation factor during neurogenesis. It binds to the insulin gene E-box and requires dimerization with another basic helix-loop-helix (bHLH) protein for efficient DNA binding.
Defects in NEUROD1 cause maturity onset diabetes of the young type VI (MODY6), a non-insulin-dependent diabetes mellitus with autosomal dominant inheritance, early adult onset, and primary defect in insulin secretion.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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