
Thermo Fisher Scientific RIOK1 Polyclonal Antibody
Human RIOK1 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% 글리세롤) 용액 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA553649
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RIOK1. Recombinant protein control fragment (Product #RP-91424) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646574 |
Product Specific Information
Immunogen sequence:
NVNDFFMRHS VAVMTVRELF EFVTDPSITH ENMDAYLSKA MEIASQRTKE ERSSQDHVDE
EVFKRAYIPR TLNEVKNYER DMDIIMKLKE EDMAMNAQQD NILYQTVTGL KKDLSGVQKV
PALLENQVEE RTCSDSEDIG SSEC- Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 84%
Target Information
FXR1 is an RNA binding protein that interacts with functionally similar proteins FMR1 and FXR2.
It may regulate intracellular transport and local translation of certain mRNAs.
These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit.
FXR1 is required for embryonic and postnatal development of muscle tissue.
Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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