Thermo Fisher Scientific IF3EI Polyclonal Antibody
Thermo Fisher Scientific IF3EI Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 기반 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 단백질 합성 개시 인자인 eIF3 복합체 연구에 활용됩니다. 고순도 Protein A 정제 및 안정적 액상 포맷 제공.
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Thermo Fisher Scientific IF3EI Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human IF3EI, amino acids 461–564 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). It stimulates mRNA recruitment to the 43S PIC and scanning for AUG recognition. The eIF-3 complex also plays a role in disassembly and recycling of post-termination ribosomal complexes, preventing premature joining of the 40S and 60S subunits. It specifically targets translation of mRNAs involved in cell proliferation, differentiation, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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