Thermo Fisher Scientific NMNAT1 Polyclonal Antibody
Rabbit polyclonal antibody against human NMNAT1, validated for Western blot. Recognizes N-terminal region (aa 50–99). Supplied as liquid, 1 mg/mL in PBS with 2% sucrose. Protein A purified, stored at −20 °C. For research use only.
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Applications
Western Blot (WB)
- Tested dilution: 1 µg/mL
- Publications: Refer to Thermo Fisher Scientific database
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human NMNAT1 (aa 50–99) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577230 |
Product Specific Information
Peptide sequence:
PVGDAYKKKG LIPAYHRVIM AELATKNSKW VEVDTWESLQ KEWKETLKVL
Sequence homology:
Cow 93%; Dog 93%; Goat 79%; Guinea Pig 100%; Horse 93%; Human 100%; Mouse 100%; Rabbit 100%; Rat 100%; Zebrafish 86%
Target Information
The coenzyme NAD and its derivatives are involved in numerous metabolic redox reactions and are utilized in protein ADP‑ribosylation, histone deacetylation, and certain Ca²⁺ signaling pathways.
NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.
(Zhang et al., 2003 [PubMed 12574164]; supplied by OMIM)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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