Thermo Fisher Scientific PSMB4 Polyclonal Antibody
Thermo Fisher Scientific의 PSMB4 Polyclonal Antibody는 인간 Proteasome β4 서브유닛을 인식하는 Rabbit IgG 항체로, WB, IHC, IP 등 다양한 실험에 사용 가능. 액상 형태, 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 214 and 264 of Human Proteasome (prosome, macropain) Subunit, beta type, 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure.
The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings contain 7 alpha subunits and 2 rings contain 7 beta subunits.
Proteasomes are distributed throughout eukaryotic cells at high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
An essential function of the immunoproteasome is the processing of class I MHC peptides.
This gene encodes a member of the proteasome B-type family (T1B family), which is a 20S core beta subunit.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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