Thermo Fisher Scientific PIK3R6 Polyclonal Antibody
Human PIK3R6 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품입니다.
- 카탈로그번호
- PA554689
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PIK3R6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PIK3R6. Recombinant protein control fragment (Product # RP-93428) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645564 |
Product Specific Information
Immunogen sequence:
PAAPVTDHTC LNVNVTEVVK SSNLAGKSFS TVTNTFRTNN IQIQSRDQRL LTLSLDKDDQ RTFRDVVRFE VAPCPEPCSG AQKSKAPWLN LHGQQEVEAI KAKPKP
Highest antigen sequence identity to the following orthologs:
- Mouse: 71%
- Rat: 67%
Target Information
p87PIKAP (p87 PI3K adapter protein), also known as PIK3R6 (phosphoinositide-3-kinase, regulatory subunit 6), p84, or HsT41028, is a 754 amino acid cytoplasmic protein that functions as a regulatory subunit of the PI 3-kinase p110 complex.
It is expressed in heart, dendritic cells, macrophages, and neutrophils, where it drives PI 3-kinase p110 activation, interacts with PDE3B, and facilitates scaffolding interactions.
The gene encoding p87PIKAP maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes more than 1,200 genes. Two key tumor suppressor genes associated with chromosome 17 are p53 and BRCA1.
- p53 maintains genomic integrity by regulating DNA repair and apoptosis.
- BRCA1 is involved in DNA repair and is linked to early-onset breast and ovarian cancers, as well as cancers of the colon, prostate, and fallopian tubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.