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Thermo Fisher Scientific eIF4E2 Monoclonal Antibody (OTI1F2)
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Western blot, IHC, Flow cytometry에 적합한 eIF4E2 단클론 항체. Human 시료에 반응하며, Mouse IgG1 형식의 액상 항체. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol buffer 구성. 연구용 전용 제품.
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마지막 업데이트 2025. 08. 03. 오후 01:06
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Thermo Fisher Scientific MA525413 eIF4E2 Monoclonal Antibody (OTI1F2) 100 ul pk판매 단위 pk ·
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775,200원VAT 포함 852,720원
Thermo Fisher Scientific · Thermo Fisher Scientific eIF4E2 Monoclonal Antibody (OTI1F2)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F2 |
| Immunogen | Full length human recombinant protein of EIF4E2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724246 |
Target Information
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:9582349, PubMed:17368478, PubMed:25624349).
Acts as a repressor of translation initiation (PubMed:22751931).
In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and blocking assembly of eIF4F at the cap.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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