Thermo Fisher Scientific SCG5 Polyclonal Antibody
SCG5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성을 제공. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCG5. Recombinant protein control fragment (Product #RP-108636). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2857131 |
Product Specific Information
Immunogen sequence:
AYSPRTPDRV SEADIQRLLH GVMEQLGIAR PRVEYPAHQA MNLVGPQSIE GGAHE
Target Information
Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway.
Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated.
Also required for cleavage of PCSK2 but does not appear to be involved in its folding.
Plays a role in regulating pituitary hormone secretion.
The C-terminal peptide inhibits PCSK2 in vitro.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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