Thermo Fisher Scientific CACNA2D3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 900-1040 of human CACNA2D3 (NP_0608682) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CACNA2D3,uniProtId:Q8IZS8-1,ncbiNodeId:9606,antigenRange:900-1040,antigenLength:1091,antigenImageFileName:PA5-87802_CACNA2D3_Q8IZS8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87802_CACNA2D3_Q8IZS8-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.52 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804420

Product Specific Information

Immunogen sequence: LYDYQAMCRA NKESSDGAHG LLDPYNAFLS AVKWIMTELV LFLVEFNLCS WWHSDMTAKA QKLKQTLEPC DTEYPAFVSE RTIKETTGNI ACEDCSKSFV IQQIPSSNLF MVVVDSSCLC ESVAPITMAP IEIRYNESLK C; Positive Samples: U-87 MG, HeLa, Hep G2, Mouse brain, Rat brain; Cellular Location: Membrane, Single-pass type I membrane protein

Target Information

CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.