Thermo Fisher Scientific CD162 (Selectin P Ligand) Recombinant Rabbit Monoclonal Antibody (PSGL1/8192R)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

2 µg/mL

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PSGL1/8192R

Immunogen

Recombinant full-length human SELPLG (CD162) protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD162 (PSGL-1),uniProtId:Q14242-1,ncbiNodeId:9606,antigenRange:1-412,antigenLength:412,antigenImageFileName:6404-RBM5-P1ABX_CD162_PSGL-1_Q14242-1_Rabbit.svg,antigenImageFileNamePDP:6404-RBM5-P1ABX_CD162_PSGL-1_Q14242-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.