
Thermo Fisher Scientific NIR Polyclonal Antibody
Rabbit polyclonal antibody recognizing human Novel INHAT Repressor (NIR). Validated for WB, IHC, IHC(P), and IP applications. Supplied as liquid, unconjugated form at 1 mg/mL concentration. Recommended storage at 4°C, shelf life 1 year.
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Thermo Fisher Scientific NIR Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 699 to 749 of human Novel INHAT Repressor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The INHAT (inhibitor of acetyltransferases) complex binds to histones and masks them from being substrates for acetyltransferase. Endogenous INHAT subunits, including the Set/TAF-Iβ oncoprotein, associate with chromatin in vivo and can block coactivator-mediated transcription when transfected in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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