Thermo Fisher Scientific Epstein Barr Virus Antibody Cocktail

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:25-1:50

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Product Specifications

Species Reactivity

Virus

Published species

Virus

Host/Isotype

Mouse / IgG1, kappa

Class

Cocktail

Type

Antibody

Clone

CS1, CS2, CS3, CS4

Immunogen

EBV-encoded recombinant latent membrane protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10984154

Product Specific Information

MA5-12172 targets Epstein-Barr Virus in IHC (P) applications and shows reactivity with Bacteria samples.

The MA5-12172 immunogen is eBV-encoded recombinant latent membrane protein.

Target Information

Epstein-Barr virus (EBV) is a human herpes virus, which is associated with conditions such as Hodgkins disease and Burkitts Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.