Thermo Fisher Scientific HORMAD2 Polyclonal Antibody
HORMAD2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간 샘플 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 안정적 보관 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human HORMAD2 (aa 35–84) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606655 |
Product Specific Information
- Peptide Sequence: VKKLFATSIS CITYLRGLFP ESSYGERHLD DLSLKILRED KKCPGSLHII
- Sequence Homology:
Cow: 100% | Dog: 100% | Horse: 100% | Human: 100% | Mouse: 79% | Pig: 100% | Rabbit: 100% | Rat: 100% | Yeast: 82%
Target Information
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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