Thermo Fisher Scientific H-cadherin Monoclonal Antibody (OTI3H6)
H-cadherin 단백질을 인식하는 마우스 단일클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol 완충액에 보관됩니다. 연구용 전용 시약으로 안정적인 신호 검출이 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Full length human recombinant protein of CDH13 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.41 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723226 |
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, catalyzing the removal of the 3′ trailer from precursor tRNAs. It interacts with activated Smad2 and its nuclear partner forkhead box H1 (FAST-1). Reduced expression can suppress TGF-beta–induced growth arrest, and mutations in this gene are associated with increased prostate cancer risk. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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