Thermo Fisher Scientific RAMP1 Polyclonal Antibody
RAMP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간, 마우스, 랫트 반응성. IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse RAMP-1, amino acids 118–148 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene belongs to the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs).
RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.
They are required for transporting calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
CRLR can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor depending on which RAMP family members are expressed.
In the presence of RAMP1, CRLR functions as a CGRP receptor.
RAMP1 is involved in terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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