Thermo Fisher Scientific NDRG1 Polyclonal Antibody
Rabbit polyclonal antibody targeting NDRG1 protein for Western blot applications. Synthetic peptide immunogen, unconjugated liquid form, stored at -20°C. Suitable for research use in studies of cholesterol transport, stress response, and cell different...
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide (382 GNSAGPKSMEVSC 394) of NDRG1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2540684 |
Target Information
NDRG1 is a 394-amino-acid cytoplasmic protein belonging to the NDRG family. It interacts with APO A-I and A-II and plays roles in HDL-mediated cholesterol transport, stress responses, hormone responses, cell growth, and differentiation.
Defects in NDRG1 cause Charcot-Marie-Tooth disease type 4D (CMT4D), characterized by reduced nerve conduction velocities, segmental demyelination and remyelination with onion bulb formations, progressive distal muscle atrophy and weakness, absent deep tendon reflexes, and hollow feet.
NDRG1 acts as a growth inhibitory marker of differentiation and is expressed in placental membranes, prostate, kidney, small intestine, ovary tissues, colon, and luminal border cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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