Thermo Fisher Scientific COMMD9 Polyclonal Antibody
Rabbit polyclonal antibody targeting human COMMD9 protein. Validated for WB, IHC, and ICC/IF applications. Unconjugated liquid form with 0.1 mg/mL concentration. Suitable for research use in studies of NF-κB regulation and sodium channel modulation.
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Thermo Fisher Scientific COMMD9 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (IHC) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COMMD9 (amino acids 41–171, length 198) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640042 |
Product Specific Information
Immunogen sequence:
KLLDVTCSSL SVTQEEAEEL LQALHRLTRL VAFRDLSSAE AILALFPENF HQNLKNLLTK IILEHVSTWR TEAQANQISL PRLVDLDWRV DIKTSSDSIS RMAVPTCLLQ MKIQEDPSLC GDKPSISAVT V
Highest antigen sequence identity to orthologs:
- Mouse: 89%
- Rat: 95%
Target Information
COMMD9 may modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).
It may down-regulate activation of NF-kappa-B (PubMed:15799966).
Also modulates Na(+) transport in epithelial cells by regulating apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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