Thermo Fisher Scientific ALKBH7 Polyclonal Antibody
Thermo Fisher Scientific의 ALKBH7 Polyclonal Antibody는 인간 ALKBH7 단백질을 인식하는 토끼 IgG 항체로, IHC(P) 등에 사용됩니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 40% 글리세롤과 0.02% 아지드가 포함되어 있습니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ALKBH7 (Product #RP-96561) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637870 |
Product Specific Information
- Immunogen sequence:
GQTLLSSVHV LDLEARGYIK PHVDSIKFCG ATIAGLSLLS PSVMRLVHTQ EPGEWLELLL EPGSLYILRG SARYDFSHEI LRDEESFFG - Highest antigen sequence identity to orthologs:
- Mouse: 90%
- Rat: 91%
Target Information
ALKBH7 (alkB, alkylation repair homolog 7), also known as SPATA11, is a 221 amino acid protein belonging to the alkB family. ALKBH7 is one of many homologs of the Escherichia coli protein AlkB. AlkB protects DNA and RNA against damage from environmental methylating compounds by reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions through oxidative demethylation. The enzyme utilizes ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent.
ALKBH7 is encoded by a gene located on human chromosome 19, which contains over 63 million bases and approximately 1,400 genes, known for its high gene density.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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