Thermo Fisher Scientific MBL2 Polyclonal Antibody
인체 MBL2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ELISA 등에 적합합니다. 고순도 Affinity Chromatography로 정제되었으며, PBS/glycerol buffer에 보존됩니다. 면역 방어 관련 연구용으로 사용됩니다.
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Thermo Fisher Scientific MBL2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–248 of human MBL2 (NP_000233.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.21 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855358 |
Product Specific Information
Immunogen sequence:
ETVTCEDAQK TCPAVIACSS PGINGFPGKD GRDGTKGEKG EPGQGLRGLQ GPPGKLGPPG NPGPSGSPGP KGQKGDPGKS PDGDSSLAAS ERKALQTEMA RIKKWLTFSL GKQVGNKFFL TNGEIMTFEK VKALCVKFQA SVATPRNAAE NGAIQNLIKE EAFLGITDEK TEGQFVDLTG NRLTYTNWNE GEPNNAGSDE DCVLLLKNGQ WNDVPCSTSH LAVCEFPI
Target Information
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose, and N-acetylglucosamine on various microorganisms and activates the lectin complement pathway. MBL2 also binds to late apoptotic and necrotic cells, facilitating their uptake by macrophages, but not to early apoptotic cells. Additionally, MBL2 may bind DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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