Thermo Fisher Scientific RSK3 Polyclonal Antibody
RSK3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 4°C 보관. 연구용으로만 사용.
- 카탈로그번호
- A304244Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RSK3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 25 to 75 of Human Ribosomal S6 Kinase 3 (RSK3, UniProt ID: Q15349-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It acts as a signal-transducing intermediate in cellular responses to various growth factors. RSK3 is expressed in many tissues, with higher levels in lung and skeletal muscle.
The p90 ribosomal S6 kinases (RSK1–4) are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may influence G-protein coupled signaling regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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