Thermo Fisher Scientific Doublecortin Monoclonal Antibody (01)
인간 Doublecortin/DCX 단백질을 인식하는 단클론 항체입니다. 면역세포화학(ICC/IF)에 적합하며, 단백질 A로 정제된 액상 형태입니다. 1 mg/mL 농도로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA543xxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Doublecortin Monoclonal Antibody (01)
Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 01 |
| Immunogen | Recombinant Human Doublecortin/DCX Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912179 |
Product Specific Information
Specificity: Human Doublecortin/DCX
Target Information
In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein that directs neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains that bind microtubules and interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase. This interaction is essential for proper microtubule function in the developing cortex. Mutations in the DCX gene are a cause of X-linked lissencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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