Thermo Fisher Scientific MRCK gamma Polyclonal Antibody
Rabbit polyclonal antibody against human MRCK gamma, validated for IHC (Paraffin). Recombinant protein immunogen with high specificity. Suitable for cytoskeletal and kinase signaling studies. Supplied as liquid, 0.2 mg/mL, stored at 4°C or -20°C.
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRCK gamma. Recombinant protein control fragment (Product # RP-95077) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644099 |
Product Specific Information
- Immunogen sequence:
PSNSLIPFLS FRSSEKDSAK DPGISGEATR HGGEPDLRPE GRRSLRMGAV FPRAPTANTA STEGLPAKPG SH - Highest antigen sequence identity:
- Mouse: 72%
- Rat: 71%
Target Information
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization and contributes to the actomyosin contractility required for cell invasion through regulation of MYPT1 and MLC2 phosphorylation.
It belongs to the AGC protein kinase family, DMPK subfamily, and contains:
- N-terminal kinase domain
- Coiled-coil domains (including kinase inhibitory motif, KIM)
- Variable region
- Cysteine-rich domain
- Pleckstrin homology (PH) domain
- Citron homology (CNH) domain
- C-terminal CDC42/RAC interactive binding (CRIB) domain
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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