Thermo Fisher Scientific CD298 Recombinant Rabbit Monoclonal Antibody (23GB4740)

Applications

• Western Blot (WB): 1:1,000–1:5,000

Product Specifications

Target Information

The protein encoded by this gene belongs to the family of Na⁺/K⁺ and H⁺/K⁺ ATPase beta chain proteins, and to the subfamily of Na⁺/K⁺-ATPases. Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability of nerve and muscle cells.

This enzyme consists of two subunits: a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates the number of sodium pumps transported to the plasma membrane through assembly of alpha/beta heterodimers. The glycoprotein subunit of Na⁺/K⁺-ATPase is encoded by multiple genes, and this gene encodes a beta 3 subunit. A pseudogene for this gene exists on chromosome 2.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.