Thermo Fisher Scientific SOAT1 Recombinant Rabbit Monoclonal Antibody (8J8E6)
Recombinant rabbit monoclonal antibody against human SOAT1. Validated for WB and ELISA. High specificity and reproducibility. Supplied in liquid form with Protein A purification. For research use only.
- 카탈로그번호
- MA555558
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SOAT1 Recombinant Rabbit Monoclonal Antibody (8J8E6)
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8J8E6 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–104 of human SOAT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.03 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
MVGEEKMSLR NRLSKSRENP EEDEDQRNPA KESLETPSNG RIDIKQLIAK KIKLTAEAEE LKPFFMKEVG SHFDDFVTNL IEKSASLDNG GCALTTFSVL EGEK
Target Information
SOAT1 (sterol O-acyltransferase-1), also known as ACAT1, is a homotetrameric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A (acyl-CoA). The human SOAT1 gene maps to chromosome 1 and encodes a protein localized to the endoplasmic reticulum (ER) in tissues such as liver, kidney, adrenal glands, and macrophages.
SOAT1 plays a key role in cellular cholesterol homeostasis, foam cell formation, and atherosclerosis progression. Several SOAT inhibitors have been developed for potential therapeutic use in atherosclerosis.
SOAT2 (sterol O-acyltransferase-2), also known as ACAT2, participates in lipoprotein assembly and cholesterol esterification in mammalian cells. It is an integral ER membrane protein of intestinal cells, and SOAT2 deficiency is associated with severe mental retardation and hypotonus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.