Thermo Fisher Scientific NCAPD2 Polyclonal Antibody
Thermo Fisher Scientific의 NCAPD2 폴리클로날 항체는 인간 NCAPD2 단백질을 검출하는 연구용 항체로, WB 및 IHC(P) 응용에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 -20°C 보관됩니다. 세포 내 응축 복합체 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human non-SMC condensin I complex, subunit D2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635820 |
Product Specific Information
This antibody detects endogenous levels of total NCAPD2 protein.
Target Information
Regulatory subunit of the condensin complex, required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex introduces positive supercoils into relaxed DNA and converts nicked DNA into positive knotted forms. It may target the condensin complex to DNA via its C-terminal domain and promote resolution of double-strand DNA catenanes between sister chromatids. Essential for accurate mitotic chromosome condensation during neurogenesis, influencing neuron pool and cortex size.
[UniProt]
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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