Thermo Fisher Scientific HNF1-alpha Polyclonal Antibody
HNF1-alpha 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human에 반응하며 Mouse와 Rat에도 예측 반응. WB, IHC, IP 등 다양한 어플리케이션에 사용 가능. 항원 친화 크로마토그래피로 정제된 고품질 항체로 연구용에 적합.
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Thermo Fisher Scientific HNF1-alpha Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475–525 of human HNF1 Homeobox A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of WHS or Pitt-Rogers-Danks syndrome.
The encoded protein can react with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting its potential as a target for cancer immunotherapy. It is also a member of the NELF (negative elongation factor) complex, participating in RNA polymerase II transcription elongation regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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