Thermo Fisher Scientific RALBP1 Monoclonal Antibody (OTI1C8), TrueMAB
RALBP1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, ICC/IF, Flow, IP 등 다양한 실험에 적합. HEK293T 세포에서 생산된 완전 길이 인간 RALBP1 단백질을 면역원으로 사용. 고순도 친화 크로마토그래피 정제, 안정적 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific RALBP1 Monoclonal Antibody (OTI1C8), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C8 |
| Immunogen | Full length human recombinant protein of human RALBP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.73 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RALBP1 specifically activates hydrolysis of GTP bound to RAC1 and CDC42, but not RALA.
It mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX), serving as the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.
RALBP1 can catalyze transport of glutathione conjugates and xenobiotics, contributing to multidrug resistance.
It acts as a scaffold protein, organizing endocytotic complexes during interphase and interacting with CDC2 to regulate endocytosis. One known substrate is EPN1/Epsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA500890_RALBP1_Q15311-1_House_mouse.svg, TA500890_RALBP1_Q15311-1_House_mouse_PDP.jpeg)
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