Thermo Fisher Scientific FXYD2 Polyclonal Antibody
FXYD2 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. 면역세포염색(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 완충액(40% glycerol) 보존, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FXYD2. Recombinant protein control fragment (Product # RP-107318) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662978 |
Product Specific Information
- Immunogen sequence: MTGLSMDGGGS PKGDVDPFYY DYE
- Antigen sequence identity: Mouse 46%, Rat 63%
Target Information
The human FXYD2 (pronounced fix-id) gene maps to chromosome 11q23 and encodes the gamma subunit of Na/K-ATPase (NKA).
FXYD2 gamma subunit modulates NKA activity by inducing ion channel activity.
The mammalian FXYD family maintains Na⁺ and K⁺ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na⁺ reabsorption, muscle contraction, and neuronal excitability.
FXYDs are single-span membrane proteins that share a 35 amino acid signature domain beginning with the sequence PFXYD and containing 7 invariant and 6 conserved amino acids.
Other members of the FXYD family include FXYD1 (PLM), FXYD3 (Mat8), FXYD4 (CHIF), and FXYD5 (RIC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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