Thermo Fisher Scientific Contactin 2 Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 CNTN2 폴리클로날 항체. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체. PBS/glycerol buffer에 보관하며 -20°C에서 안정적 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CNTN2 (Accession Q02246), corresponding to amino acid residues S114–L164. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850975 |
Product Specific Information
Antibody detects endogenous levels of total CNTN2.
Target Information
Contactin 2 (CNTN2, also known as transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system.
It belongs to the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol anchor, six immunoglobulin (Ig)-like domains, and four Fibronectin type III (FNIII)-like domains.
Contactin 2 is predominantly expressed during neural development on axonal membranes, guiding commissural axons without promoting their growth.
It binds with NgCAM in cis within the same membrane. The heterophilic binding sites (Contactin 2/NgCAM and Contactin 2/NrCAM) are localized to the first four Ig domains, while the homophilic binding site (Contactin 2/Contactin 2) resides in the FNIII domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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